The Drug Controller General Of India (Dcgi) Has Approved Zydus Cadila’s New Drug Application (Nda) To Cater To Growing Demand From Chronic Liver Diseases Therapeutics Market

Chronic Liver Diseases Therapeutics Market

 North America is projected to lead the global chronic liver disease therapeutics market due to the increasing focus of players on collaboration strategies to expand their business. For instance, in April 2020, Alnylam Pharmaceuticals, Inc. collaborated with Dicerna Pharmaceuticals, Inc. for the development and commercialization of investigational RNAi therapeutics for the treatment of alpha-1 antitrypsin deficiency-associated liver disease.

The global chronic liver diseases therapeutics market is expected to witness significant growth owing to the growing prevalence of liver disease around the globe. According to the European Association for the Study of the Liver, the liver disease accounts for approximately 2 million deaths per year worldwide, 1 million due to complications of cirrhosis and 1 million due to viral hepatitis and hepatocellular carcinoma. Thus a high number of patients with liver disease such as cirrhosis is propelling the growth of the chronic liver diseases therapeutics market. Additionally, a growing number of clinical trials of new therapies are again expected to support the market growth. For instance, in March 2018, the U.S. FDA granted Orphan Drug Designation for Protagonist Therapeutics, Inc.’s PTG-300; a subcutaneous injectable in the clinical development stage for the potential treatment of beta-thalassemia and liver fibrosis.

According to data published by the UK Research Alcohol Association in 2017, around 7,700 people die from the alcohol-related liver disease each year in the U.K. The global chronic liver diseases therapeutics market is witnessing significant industry growth both in developed countries like the USA and UK and in developing countries like India, Brazil, Malaysia, China, and Indonesia.


    1. In March 2020, The Drug Controller General of India (DCGI) has approved Zydus Cadila’s new drug application (NDA) for Saroglitazar for treatment of Non-Cirrhotic, Non-Alcoholic SteatoHepatitis (NASH) in India. NASH is a progressive disease of the liver. 

    2. In May 2018, The U.S. Food and Drug Administration approved Doptelet (avatrombopag) tablets to treat low blood platelet count (thrombocytopenia) in adults with chronic liver disease who are scheduled to undergo a medical or dental procedure

    3. In October 2018, Novartis announced that it has entered into a clinical development agreement with Pfizer which will include a study combining tropifexor and one or more Pfizer compounds for the treatment of NASH


There are a number of different types of liver disease, including Hepato-megaly (liver cancer) and Hepatomegaly (enlargement). The most common cause of this disease is alcohol abuse, but some other causes can include Hereditary Factors and hepatitis B and C infections

Location: India

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