Lentiviral Vectors Market Growth Is Driven by Increasing Research and Development Activities

Lentiviral Vectors Market

 Lentiviral vectors is a technique in which genetically engineered viruses can be introduced, modified, or even deleted from living organisms with the help of lentivirus. These viruses are then injected into various target organs where they multiply and reproduce. However, for this technology to work, the natural genetic material, i.e., the DNA of the recipient organism, must be in perfect order. Lentivirus are a family of viruses that are responsible for chronic and deadly diseases in the human and other mammalian species. The best known lentivirus is human immunodeficiency virus (HIV), which causes AIDS. Thus, the growth of the lentiviral vectors market can be attributed to the increasing prevalence of HIV.

According to the United Nations Programme on HIV/AIDS (UNAIDS), worldwide, around 38 million people were living with HIV, around 1.7 million people became newly infected with HIV, and around 690,000 people died from AIDS-related illnesses in 2019. Thus, increasing prevalence of HIV, as well as Alzheimer’s, and amyotrophic lateral sclerosis, β-thalassemia, and sickle cell disease is expected to drive the lentiviral vectors market growth. Lentiviral vectors are highly efficient for in vivo gene delivery for gene therapies. These vectors can also be used to treat variety of rare genetic disorders; Metachromatic Leukodystrophy, X-linked severe combined immunodeficiency, X-linked Adrenoleukodystrophy, and β-thalassemia.

Moreover, lentiviral vectors are used in both gene therapy and research applications. Thus, with increasing research and development for gene therapies, the demand for lentiviral vectors is also increasing. For instance, in October 2019, Avrobio Inc. started a phase I and phase II trial for gene therapy, including lentiviral vector, for patients with type 1 Gaucher disease; a rare, inherited metabolic disorder. Moreover, in May 2020, Avrobio revealed how lentiviral gene therapy may potentially correct Pompe disease manifestations in the muscle and the central nervous system. The aforementioned factors are also expected to augment the growth of the lentiviral vectors market.

The reason why lentiviral vector therapy is more popular than any other form of retrovirus therapy is that the process is cheaper, faster, and more effective. Moreover, lentiviral vectors have recently been used in multiple clinical trials to introduce genes into hematopoietic stem cells to correct primary hemoglobinopathies and immunodeficiencies. This in turn is expected to accelerate the lentiviral vectors market growth. However, the possibility of oncogenesis through insertional mutagenesis and potential generation of replication competent virus are the major factors restraining the lentiviral vectors market growth.

https://www.coherentmarketinsights.com/market-insight/lentiviral-vectors-market-4068

Location: India

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